2009年孤独症研究的10大成就

　　目录：

　　1、  本年度的孤独症流行病学——（The Year of Autism Epidemiology——相同的发现显示孤独症流行病率现为1%（Converging findings show autism prevalence now 1%）

　　2、  孤独症学步儿童的早期干预（Early Intervention for Toddlers with ASD ——First randomized clinical trial of early intervention for toddlers shown to be effective for improving cognition, language, and adaptive behavior）

　　3、  首项孤独症基因协作研究——使用新技术发现新的孤独症基因，与脑发育相关（New technologies lead to discovery of new autism genes involved in brain development）

　　4、  基因复制数量变异的研究揭示新的生物医学方法——首次发现泛素蛋白方法与孤独症相关（Studies of Genetic Copy Number Variations Reveal New Biological Pathways——The ubiquitin pathway is linked to autism for the first time）

　　5、  多种方法结合使用支持更加有治疗效果的假设——对于减少孤独症儿童的严重问题，药物与父母训练比药物更加有效果单独（Combined Therapies Hold Promise for More Effective Treatments——Medication and parent training are more effective for reducing serious behavioral problems in children with autism than medication alone）

　　6、  基因成果导致新的孤独症老鼠模型（老鼠携带与孤独症相关的基因变异之后表现出本障碍的某些模糊和具有特征的表现（Genetic Findings Lead to New Mouse Model of Autism——Mice carrying a mutation in a gene linked to autism display some subtle and specific features of the disorder）

　　7、  线粒体功能失调、孤独症退化与发热——线粒体功能失调和孤独症的人士被发现具有高比率的孤独症样退化（Mitochondrial Dysfunction, Autistic Regression… and Fever——Individuals with mitochondrial dysfunction and autism found to have high rate of autistic regression）

　　8、  无口语孤独症个体语言的延迟获得——Later Language Acquisition in Nonverbal Individuals with Autism——Contrary to early beliefs, individuals with autism can acquire spoken language after age five

　　9、  孤独症语言退化——失去语言技能被发现是孤独症谱系障碍儿童具有特征性的表现（Language Regression in Autism——Losing language skills is found to be specific to children with autism spectrum disorder）

　　10、  自动免疫疾病家族史与孤独症谱系障碍的关系——使用丹麦大型数据库发现孤独症与免疫系统的另一种关联（Association of Family History of Autoimmune Disease and Autism Spectrum Disorders——Use of large Danish datABAse adds another link between autism and the immune system）